sebacic acid solubility

SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. 1. Sebacic acid and hexamethylene diisocyanate react through condensation polymerization to produce Nylon 6-10. One of the largest uses of Sebacic Acid is in the manufacture of Nylon 6-10. Solubility in water: 0.25 g/L[1] 遺����援ъ“��� (HOOC)(CH2)8(COOH)��� ��댁�쇨린��곗�쇰�� ��쇳�댁�� ��곗��(���珥�瑜� 留���ㅻ�� 寃�)瑜� ��삵����� sebum������ ������������ sebacic acid濡� 紐�紐���������쇰ʼn �����댄��吏� ������ 寃���쇰�� �����ㅼ�� 遺�留���������대�� 誘몄�몃��吏���� 諛������������� ������. Water solubility Solubility in organic solvents / fat solubility Surface tension Flash point Auto flammability Flammability Explosiveness Oxidising properties Oxidation reduction potential Stability in organic solvents and identity of 2. Sebacic acid, a 10 carbon containing dicarboxylic acid (DCA), is an important precursor in the production of nylon and polyamides (PAs), primarily PA-4,10 and PA-5,10 (Chung et al. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Stable. View information & documentation regarding Sebacic acid, including CAS, MSDS & more. Sebacic Acid is a white flake or powdered crystal. Sebacic acid for synthesis. It is a conjugate acid of a sebacate (2-) and a sebacate. A weak synergistic effect was found for sebacic acid + ethanol + water mixed systems. Wash thoroughly after handling. Sebacic acid is an intermediate product of ��- oxidation of long-chain aliphatic acids. SEBACIC ACID 1 Physical and Chemical Fuction: Molecular Formula: HOOC(CH2)8COOH Molecular Weight: 202.25 It is white powder crystal, slightly dissolves in water, completely dissolved in ethanol or ether, but not in benzene. Solubilities of sebacic acid in binary ethanol + water solvent mixtures were measured by the dynamic method using a laser monitoring observation technique at a temperature range from (288 to 352) K. The mole fraction of ethanol in the solvent mixtures ranges from 0 to 1. Other identifiers. DESCRIPTION & APPLICATIONS Sebacic Acid is a white flake or powdered crystal. CopyCopied, InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14) Sebacic acid: ��ε�� ��������� 1,8 ... Foti, C.; Sammartano, S. Solubility and Activity Coefficients of Acidic and Basic Nonelectrolytes in Aqueous Salt Solutions. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH 2) 8 (CO 2 H) 2.It is a white flake or powdered solid. and has antitumor activity. Approximation models were employed for determining solubility of sebacic acid at elevated temperatures. The solubility of sebacic acid was found as 500 g L −1 in the optimum conditions at 400 K temperature, 4 min dynamic time and 28 min static time. - Find MSDS or SDS, a COA, data sheets and more information. PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. Decanedioic acid sodium salt TOP1 supplier Cas No: 17265-14-4 USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Disposal considerations Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid is a normal urinary acid. Sebacic Acid Safety Data Sheet According to Federal Register / Vol. The solubility of sebacic acid in subcritical water was investigated. The castor oil is treated with caustic soda at high temperature, for example 250 C, so that saponification, leading to the formation of ricinoleic acid, is followed by a reaction giving sebacic acid and octan-2-ol: CAS 111-20-6, EC Number 203-845-5, chemical formula HOOC(CH���)���COOH. It is a white flake or powdered solid. Human neutrophils can convert sebacic acid to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid (5-oxo-ODE). It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). Can react with active metals to form gaseous hydrogen and a metal salt. A process for preparing sebacic acid by reacting in a first step (i) linoleic acid with water catalyzed by an oleate hydratase to form 10-hydroxy-12-octadecenoic acid, … Sebazinsaeure. Organic Compound; Plasticizer; Food Toxin; Metabolite; Cosmetic Toxin; Industrial/Workplace Toxin; Animal Toxin; Natural Compound, ORL-RAT LD50 3400 mg kg-1, ORL-MUS LD50 6000 mg kg-1, P261; P280; P302+P352; P304+P340; P305+P351+P338; P312, P261-P280-P305+P351+P338-P304+P340-P405-P501a. Sebacic acid is produced from castor oil by cleavage of ricinoleic acid, which is obtained from castor oil. Solubility Slightly soluble in water. This action is mediated by the OXER1 receptor on these cells. Applications Sebacic acid is used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics and candles. About Sebacic Acid Sebracic acid is a white powdered crystal that is resolved in ethanol and ether, and it possess low water solubility. CopyCopied, CXMXRPHRNRROMY-UHFFFAOYSA-N Combustible. - Find MSDS or SDS, a COA, data sheets and more information. 2. Sebacic Acid Skin Not Available Eyes Not Available Respiratory LC50 Inhalation - rat - > 4,500 mg/m3 Ingestion Not Available Carcinogenicity IARC No components of this product present at levels greater than or equal to 0.1% It is a white flake or powdered solid. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Octanol is a byproduct. It is a white flake or powdered solid. In its pure state it is a white flake or powdered crystal. Sebacic Acid PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. Sebacic acid (CAS NO.111-20-6) is a low toxic substance, with flammability, burning will produce toxic fumes, so it should be stored in cool and dry environment, dry powder, foam, sand, carbon dioxide, water mist can be used if Solubility results of sebacic acid were observed to be highly correlated with quadratic model according to analysis of variance. Bioaccumulation/ AccumulationNo information available. Component log Pow Decanedioic acid 1.5 13. A process for preparing sebacic acid comprising in a first step reacting (i) linoleic acid with water catalyzed by an oleate hydratase to form 10-hydroxy-12-octadecenoic acid, in a second step (ii) pyrolysing the 10-hydroxy-12-octadecenoic acid to 1-octene and 10-oxo-decanoic acid, and in a third step (iii) oxidizing the 10-oxo-decanoic acid to sebacic acid. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. Herein, we present an e Sebacic acid is a derivative of castor oil. To detect the synergistic effect, solubilities of sebacic acid in 14.35 %, 36.97 %, 79.81 %, and 90.00 % mole fraction ethanol aqueous solution were determined to supplement our previous report. It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. Herein, we present an e CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41865, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, 295 deg C / 100 mm (400.5825 °C / 760 mmHg), 295 °C / 100 mm (400.5825 °C / 760 mmHg), 294.5 °C / 100 mmHg (399.9979 °C / 760 mmHg). However works on polyesters of sebacic acid are rare. Mobility Will likely be mobile in the environment due to its water solubility. text.skipToContent text.skipToNavigation. 250°C, so that saponification, leading to the formation of ricinoleic acid; is followed by a reaction giving sebacic acid and octan-2-ol Figure 18.5. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. 1272/2008 [CLP] Extra labelling to displayExtra classification(s) to display Telaglenastat (CB-839) New Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. Sebacic Acid. Sebacic acid 111-20-6 Sebacic acid 1,3,5-triazine-2,4,6-triamine salt 31970-90-8 Sebacic acid 1,3,5-triazine-2,4,6-triamine salt 94159-18-9 Sebacic acid 2,2',2''-nitrilotriethanol complex 94202-16-1 Sebacic acid 2,2',2 85030-06-4 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes.Remove contact lenses, if present and It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. Sebacic acid (8Cl) Registration dossier . Sebacic acid Description In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. SEBACIC ACID FOR SYNTHESIS Safety Data Sheet www.lobachemie.com 09/04/2015 2/8 Adverse physicochemical, human health and environmental effects No additional information available 2.2. The castor oil is treated with caustic soda at high temperature, e.g. C(CCCCC(=O)O)CCCC(=O)O The product is described as non-hazardous, though in its powdered form it can be prone to flash ignition (a typical risk in handling fine organic powders). Display Name: Sebacic acid EC Number: 203-845-5 EC Name: Sebacic acid CAS Number: 111-20-6 Molecular formula: C10H18O4 IUPAC Name: decanedioic acid Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Sebacic Acid Safety Data Sheet According to Federal Register / Vol. Sebacic Acid was named from the Latin sebaceus (tallow candle) or … [3], Sebum is a secretion by skin sebaceous glands. Currently, SA is produced exclusively from alkaline pyrolysis of castor oil. 77, No. Sebacic acid (SA) is an aliphatic ten-carbon dicarboxylic acid (1,10-decanedioic acid) with a variety of industrial applications, including the production of plasticizers, lubricants, cosmetics, and plastics. Sebacic acid is a derivative of castor oil. It is resolved in ethanol, ether and soluble slightly in water. Solubility Show More Product # Description 283258 Sebacic acid, 99%, 84809 Sebacic acid, ≥95.0% (GC), 8.00753 Sebacic acid, for synthesis, Sorry we cannot compare more than 4 products at a time. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) are a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. The solubility in 95% ethanol (100ml) is 11.7g. Sublimes slowly at 750 mm Hg when heated to melting point. Lookchem Provide Cas No.17265-14-4 Basic information: Properties,Safety Data,Sds and Other Datebase. Mobility Will likely be mobile in the environment due to its water solubility. CopyCopied, CSID:5004, http://www.chemspider.com/Chemical-Structure.5004.html (accessed 23:35, Jan 8, 2021) Sebacic Acid was named from the Latin sebaceus (tallow candle) or sebum (tallow) in reference to its use in the manufacture of candles. About Sebacic Acid Sebracic acid is a white powdered crystal that is resolved in ethanol and ether, and it possess low water solubility. 77, No. It is resolved in ethanol, ether and soluble slightly in water. Sebacic acid: Overview. An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. Incompatible with strong oxidizingagents, bases, reducing agents. Registration dossier . Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. SEBACIC ACID - GRANULAR May 13, 2010 Page 3 of 5 ===== HANDLING & STORAGE ===== HANDLING AND STORAGE: Use with adequate ventilation. Degree of solubility in water: 1 g/l 20 °C: Solubility (very soluble in) Alcohol: It has a role as a human metabolite and a plant metabolite. It is suggested that sebacic acid is converted to its 5-oxo analog during, and thereby stimulates pro-inflammatory cells to contribute to the worsening of, various inflammatory skin conditions. Sebacic Acid. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Structure, properties, spectra, suppliers and links for: Sebacic acid, 111-20-6. PubChem ChemSpider SMILES 3400 mg/kg (大鼠经口) [5] 6000 mg/kg (小鼠经口) [5] 若非注明,所有数据均出自一般条件(25 ,100 kPa)下。 An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. And dissolve as the neutralization generates a soluble salt organic and inorganic CH2 ) 8 ( CO2H ) 2 and! 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